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Georgia Institute of Technology :: News Room :: New Biosensor Detects Avian Influenza Virus Home News Room dish network smart card News Release Abby Vogel, Research News and Publications Contact Abby Vogelavogel@gatech. The horizontal purple lines are the channels on the waveguide. “The fringe pattern doesn’t look like it changes in the image, but with math we find out the speed of the light in the test channel changed creating this phase change,” explained Xu. The government procurement and solicitation opportunities in Georgia (GA) are fully searchable by industries. This causes a change in the velocity of the light traveling through the waveguide. The pattern of alternating dark and light vertical stripes, or fringes, is imaged on a simple detector. The antigen capture immunoassays can provide rapid test results, but suffer from low sensitivity and high cost. ”
In addition to Xu and Suarez, the research team included David Gottfried, who is now a senior research scientist in Georgia Tech’s Microelectronics Research Center. Having the reference channel minimizes the impact of non-specific interactions, as well as changes in temperature, pH and mechanical motion. By doing a mathematical Fourier transform, the researchers determine the degree to which the fringe patterns are in or out of step with each other, known as phase shift. edu) or John Toon (404-894-6986); E-mail: (jtoon@gatech. More specifically, light from a laser diode is coupled into an optical waveguide through a grating and travels under one sensing channel and one reference channel. In addition to being a rapid test, the biosensor is economical, field-deployable, sensitive to different viral strains and requires no labels or reagents. The Institute offers research opportunities to both undergraduate and graduate students and is home to more than 100 interdisciplinary units plus the Georgia Tech Research Institute. 5 MB Xu tested a third strain of the virus as a control. In the United States, outbreaks of the disease – primarily spread by migratory aquatic birds – have plagued the poultry industry for decades with millions of dollars in losses. Current methods of identifying infected birds include virus isolation, real-time reverse transcriptase polymerase chain reaction (RRT-PCR) and antigen capture immunoassays. Virus isolation is a sensitive technique, but typically requires five to seven days for testing. Researchers coat the sensing channel with the specific antibodies and coat the reference channel with non-specific antibodies. Non-specific binding should occur equally to both the test and reference channels and thus not affect the test results. If you do not find your business in this list, it is possible that it is in one of subcategories. News & World Report's top public universities, Georgia Tech's more than 18,000 students are enrolled in its Colleges of Architecture, Computing, Engineering, Liberal Arts, Management and Sciences. Solicitations in Georgia State (GA) listed below are published by all levels of governments, including federal government, Georgia state government, county government, city government, municipal government, local government, community government, town agencies, and government agency buyers such as college, university, school district, hospital, airports, correctional facility, water district, public utility, police and fire departments, and various regional government authorities in Georgia. Worldwide, there are many strains of avian influenza virus that cause varying degrees of clinical symptoms and illness. , Suite100
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Media Relations Contacts: Abby Vogel (404-385-3364); E-mail: (avogel@gatech. “With so many different virus subtypes, our biosensor’s ability to detect multiple strains of avian influenza at the same time is critical,” noted komodo dragon and indonesia Xu. 08 MB An electromagnetic field associated with the light beams extends above the waveguides and is very sensitive to the changes caused by antibody-antigen interactions on the waveguide surface. Results of this study were published online in August in the journal Analytical and Bioanalytical Chemistry and will be included in journal’s print edition on October16. A virulent strain of avian influenza (H5N1) has begun to threaten not only birds but humans, with more than300 infections and200 deaths reported to the World Health Organization since2003. When a liquid sample passes over the waveguides, any binding that occurs on the top of a waveguide because of viral particle attachment causes water molecules company development offshore software to be displaced. At the end of the waveguide, the light beams from the sensing and reference channels are combined to create an interference pattern. Government Bids, Government Contracts, and Government RFP Finder and Notification. The biosensor is coated with antibodies specifically designed to capture a protein located on the surface of the viral particle. The sensor utilizes the interference of light waves, a concept called interferometry, to precisely determine how many virus particles attach to the sensor’s surface. When the sensor coating was modified to collect only the other two strains, the control strain was not detected even at high concentrations. Jie Xu, a research scientist in the Georgia Tech Research Institute’s Electro-Optical Systems Laboratory, tests a sample using the optical waveguide sensor. To test the biosensor, the researchers assessed its ability to detect two avian influenza strains (H7N2 and H7N3) that previously infected poultry. Power is supplied by a nine volt battery and USB connection. Looming is the threat of a pandemic, such as the1918 Spanish flu that killed about40 million people, health officials say. Writer: Abby Vogel Analytical and Bioanalytical Chemistry article Georgia Tech Research Institute GTRI Electro-Optical Systems Laboratory (EOSL) The Georgia Institute of Technology is one of the nation's premiere research universities. Research News and Publications Office
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75 Fifth Street, N. edu) or Kirk Englehardt (404-407-7280); E-mail: (kirk. The results showed that a solution containing very few virus particles could be detected by the sensor. Suarez is providing antibodies and test samples for GTRI’s research. edu New Biosensor Detects Avian Influenza Virus Field-deployable unit detects virus in minutes, not days Atlanta (September 27, 2007) — Quick identification of avian influenza infection in poultry is critical to controlling outbreaks, but current detection methods can require several days to produce results. Tech is among the nation's top producers of women and African-American engineers. “Since this technology is already set up so that you can use multiple antibodies to detect different influenza subtypes, we are going to extend the work to include the H5 subtype. In addition, Xu is reducing the size of the prototype device to be about the size of a lunchbox and making the computer analysis software more user-friendly so that it can be field-tested in cabinet member state union two years. The only way to stop the spread of the disease is to destroy all poultry that may have been exposed to the virus. “We are continuing our collaboration and have provided additional money to Georgia Tech to move the project along faster,” added Suarez. The waveguides can be cleaned and reused building corporate retreat team dozens of times, decreasing the per-test cost of the chip fabrication.
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